node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK30975.1 | SEL19846.1 | SAMN05216208_0239 | SAMN05216208_3090 | beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.533 |
SEK30975.1 | fumC | SAMN05216208_0239 | SAMN05216208_2362 | beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.587 |
SEK30975.1 | mdh | SAMN05216208_0239 | SAMN05216208_3095 | beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.640 |
SEK30975.1 | sucC | SAMN05216208_0239 | SAMN05216208_0240 | beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Malate thiokinase large subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.977 |
SEK30975.1 | sucC-2 | SAMN05216208_0239 | SAMN05216208_3094 | beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.483 |
SEK30975.1 | sucD | SAMN05216208_0239 | SAMN05216208_0241 | beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Malate thiokinase small subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.976 |
SEK64470.1 | SEK64515.1 | SAMN05216208_1519 | SAMN05216208_1521 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |
SEK64470.1 | SEK64559.1 | SAMN05216208_1519 | SAMN05216208_1523 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase subunit C. | 0.999 |
SEK64470.1 | SEK73018.1 | SAMN05216208_1519 | SAMN05216208_1827 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.983 |
SEK64470.1 | SEL19846.1 | SAMN05216208_1519 | SAMN05216208_3090 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.863 |
SEK64470.1 | fumC | SAMN05216208_1519 | SAMN05216208_2362 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.975 |
SEK64470.1 | mdh | SAMN05216208_1519 | SAMN05216208_3095 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.946 |
SEK64470.1 | sucC | SAMN05216208_1519 | SAMN05216208_0240 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Malate thiokinase large subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.958 |
SEK64470.1 | sucC-2 | SAMN05216208_1519 | SAMN05216208_3094 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.987 |
SEK64470.1 | sucD | SAMN05216208_1519 | SAMN05216208_0241 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Malate thiokinase small subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.969 |
SEK64515.1 | SEK64470.1 | SAMN05216208_1521 | SAMN05216208_1519 | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
SEK64515.1 | SEK64559.1 | SAMN05216208_1521 | SAMN05216208_1523 | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Succinate dehydrogenase subunit C. | 0.999 |
SEK64515.1 | SEK73018.1 | SAMN05216208_1521 | SAMN05216208_1827 | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.927 |
SEK64515.1 | SEL19846.1 | SAMN05216208_1521 | SAMN05216208_3090 | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.594 |
SEK64515.1 | fumC | SAMN05216208_1521 | SAMN05216208_2362 | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.998 |