node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK39167.1 | SEL10409.1 | SAMN05216208_0537 | SAMN05216208_2700 | DnaJ domain-containing protein. | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | 0.590 |
SEK39167.1 | SEL18659.1 | SAMN05216208_0537 | SAMN05216208_3041 | DnaJ domain-containing protein. | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | 0.476 |
SEK39167.1 | SEL31252.1 | SAMN05216208_0537 | SAMN05216208_3406 | DnaJ domain-containing protein. | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | 0.997 |
SEK39167.1 | clpB | SAMN05216208_0537 | SAMN05216208_2127 | DnaJ domain-containing protein. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.779 |
SEK39167.1 | clpP | SAMN05216208_0537 | SAMN05216208_0914 | DnaJ domain-containing protein. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.572 |
SEK39167.1 | dnaK | SAMN05216208_0537 | SAMN05216208_1509 | DnaJ domain-containing protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.997 |
SEK39167.1 | groS | SAMN05216208_0537 | SAMN05216208_2902 | DnaJ domain-containing protein. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.761 |
SEK39167.1 | grpE | SAMN05216208_0537 | SAMN05216208_1902 | DnaJ domain-containing protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.933 |
SEL10409.1 | SEK39167.1 | SAMN05216208_2700 | SAMN05216208_0537 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | DnaJ domain-containing protein. | 0.590 |
SEL10409.1 | SEL31252.1 | SAMN05216208_2700 | SAMN05216208_3406 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | 0.503 |
SEL10409.1 | clpB | SAMN05216208_2700 | SAMN05216208_2127 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.820 |
SEL10409.1 | dnaJ | SAMN05216208_2700 | SAMN05216208_1510 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.476 |
SEL10409.1 | dnaK | SAMN05216208_2700 | SAMN05216208_1509 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.503 |
SEL10409.1 | grpE | SAMN05216208_2700 | SAMN05216208_1902 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.515 |
SEL18659.1 | SEK39167.1 | SAMN05216208_3041 | SAMN05216208_0537 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | DnaJ domain-containing protein. | 0.476 |
SEL18659.1 | SEL31252.1 | SAMN05216208_3041 | SAMN05216208_3406 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | 0.536 |
SEL18659.1 | clpB | SAMN05216208_3041 | SAMN05216208_2127 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.822 |
SEL18659.1 | dnaJ | SAMN05216208_3041 | SAMN05216208_1510 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.586 |
SEL18659.1 | dnaK | SAMN05216208_3041 | SAMN05216208_1509 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.536 |
SEL18659.1 | grpE | SAMN05216208_3041 | SAMN05216208_1902 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.631 |