STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEL19475.1L-lactate dehydrogenase (cytochrome). (387 aa)    
Predicted Functional Partners:
SEL13634.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
    
 0.939
SEK57381.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.923
SEL01207.1
L-lactate dehydrogenase (cytochrome).
  
  
 
0.917
SEL01238.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.912
SEK73018.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.911
SEK67006.1
Pyruvate, orthophosphate dikinase.
     
 0.910
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.805
SEK75003.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
    
 0.795
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
 0.780
SEK77109.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
    
 0.780
Your Current Organism:
Roseovarius nanhaiticus
NCBI taxonomy Id: 573024
Other names: CCTCC AB 208317, DSM 29590, LMG 24840, LMG:24840, MCCC 1A03543, R. nanhaiticus, Roseovarius nanhaiticus Wang et al. 2010, Roseovarius sp. NH52J, strain NH52J
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