STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
phnW2-aminoethylphosphonate-pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (392 aa)    
Predicted Functional Partners:
SEL25475.1
Phosphonoacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
  0.954
SEL25495.1
Phosphonoacetate hydrolase.
 
   
 0.934
SEL25547.1
Aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.850
SEL25442.1
4-aminobutyrate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
    0.811
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.792
SEL25629.1
iron(III) transport system substrate-binding protein.
 
  
 0.771
SEL25569.1
iron(III) transport system permease protein.
 
     0.756
SEL25396.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.747
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.713
SEL10001.1
Phosphoserine phosphatase.
   
 0.713
Your Current Organism:
Roseovarius nanhaiticus
NCBI taxonomy Id: 573024
Other names: CCTCC AB 208317, DSM 29590, LMG 24840, LMG:24840, MCCC 1A03543, R. nanhaiticus, Roseovarius nanhaiticus Wang et al. 2010, Roseovarius sp. NH52J, strain NH52J
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