STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL52894.1Protein of unknown function DUF815; KEGG: hor:Hore_15640 predicted ATPase (AAA+ superfamily); PFAM: protein of unknown function DUF815; AAA ATPase central domain protein; SMART: AAA ATPase. (417 aa)    
Predicted Functional Partners:
ADL52893.1
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: cpy:Cphy_3205 NAD-dependent glycerol-3-phosphate dehydrogenase domain-containing protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.512
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.442
ADL52892.1
PFAM: regulatory protein LacI; KEGG: cpy:Cphy_2278 LacI family transcription regulator.
       0.439
ADL50113.1
TIGRFAM: chorismate mutase; KEGG: ckr:CKR_0706 hypothetical protein; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein.
       0.422
ADL52895.1
KEGG: eel:EUBELI_01363 hypothetical protein.
       0.407
Your Current Organism:
Clostridium cellulovorans
NCBI taxonomy Id: 573061
Other names: C. cellulovorans 743B, Clostridium cellulovorans 743B, Clostridium cellulovorans str. 743B, Clostridium cellulovorans strain 743B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.