Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADG13472.1KEGG: mvu:Metvu_0911 transcriptional regulator, TrmB; PFAM: domain of unknown function DUF1745; transcriptional regulator TrmB; SMART: domain of unknown function DUF1745. (504 aa)    
Predicted Functional Partners:
ADG13470.1
KEGG: mja:MJ1437 L-2-haloalkanoic acid dehalogenase isolog; TIGRFAM: HAD superfamily (subfamily IA) hydrolase, TIGR02253; HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase.
 
     0.628
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
     0.622
ADG13370.1
PFAM: protein of unknown function DUF505; KEGG: mja:MJ1355 hypothetical protein.
  
     0.580
ADG13471.1
PFAM: Energy-converting hydrogenase B, subunit P; KEGG: mfe:Mefer_0182 energy-converting hydrogenase B, subunit P.
       0.551
ADG13208.1
KEGG: mvu:Metvu_1510 PKD domain containing protein; PFAM: PKD domain containing protein; SMART: PKD domain containing protein.
  
   
 0.454
ADG13426.1
KEGG: mvu:Metvu_1542 amino acid permease-associated region.
 
     0.431
ADG12855.1
PFAM: D-glucuronyl C5-epimerase domain protein; KEGG: mfe:Mefer_0292 D-glucuronyl C5-epimerase domain protein.
  
     0.410
Your Current Organism:
Methanocaldococcus infernus
NCBI taxonomy Id: 573063
Other names: M. infernus ME, Methanocaldococcus infernus DSM 11812, Methanocaldococcus infernus ME, Methanocaldococcus infernus str. ME, Methanocaldococcus infernus strain ME
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