STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG13610.1PFAM: peptidase U62 modulator of DNA gyrase; KEGG: mvu:Metvu_1624 peptidase U62 modulator of DNA gyrase. (409 aa)    
Predicted Functional Partners:
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; KEGG: mvu:Metvu_0390 glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain.
       0.741
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.610
ADG13608.1
PFAM: PfkB domain protein; KEGG: mfe:Mefer_1313 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
     
 0.579
ADG13607.1
TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; KEGG: mja:MJ0617 tartrate dehydratse, subunit beta (TtdB); PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
       0.563
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.563
ADG13003.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: mja:MJ1625 hypothetical protein.
   
    0.538
ADG13604.1
TIGRFAM: arsenite-activated ATPase ArsA; KEGG: mvu:Metvu_0526 arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase.
 
     0.538
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
     0.480
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
     0.479
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
     0.477
Your Current Organism:
Methanocaldococcus infernus
NCBI taxonomy Id: 573063
Other names: M. infernus ME, Methanocaldococcus infernus DSM 11812, Methanocaldococcus infernus ME, Methanocaldococcus infernus str. ME, Methanocaldococcus infernus strain ME
Server load: low (14%) [HD]