STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADG13890.1KEGG: mfe:Mefer_0350 DNA helicase; TIGRFAM: DNA helicase; SMART: DEAD-like helicase. (639 aa)    
Predicted Functional Partners:
ADG13700.1
RNA-metabolising metallo-beta-lactamase; KEGG: mja:MJ0162 putative mRNA 3'-end processing factor 3; PFAM: RNA-metabolising metallo-beta-lactamase; SMART: beta-lactamase domain protein.
   
 0.931
ADG13059.1
KEGG: mja:MJ0920 GTP-binding protein homologue (YphC); TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related.
   
 0.883
ADG13892.1
PFAM: methyltransferase small; KEGG: mfe:Mefer_1472 methyltransferase small.
   
 0.805
eif2a
Translation initiation factor 2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
   
 
 0.797
ADG13153.1
KEGG: mvu:Metvu_0999 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PEGA domain protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain.
  
 0.784
rpl40e
KEGG: mfe:Mefer_1082 hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
 0.762
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
     
 0.761
ADG13893.1
PFAM: phosphoesterase RecJ domain protein; TrkA-N domain protein; phosphoesterase DHHA1; KEGG: mfe:Mefer_1325 TrkA-N domain protein.
 
     0.721
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 0.705
rpl14e
PFAM: Ribosomal protein L14; KEGG: mfe:Mefer_0949 hypothetical protein; Belongs to the eukaryotic ribosomal protein eL14 family.
    
 0.681
Your Current Organism:
Methanocaldococcus infernus
NCBI taxonomy Id: 573063
Other names: M. infernus ME, Methanocaldococcus infernus DSM 11812, Methanocaldococcus infernus ME, Methanocaldococcus infernus str. ME, Methanocaldococcus infernus strain ME
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