Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23856.1TIGRFAM: methanogen marker protein 4. (241 aa)    
Predicted Functional Partners:
ACV23857.1
TIGRFAM: methanogenesis marker protein 12; Belongs to the UPF0285 family.
 
     0.987
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
    0.956
ACV23854.1
Hypothetical protein.
       0.773
ACV23913.1
TIGRFAM: methanogenesis marker protein 11; PFAM: domain of unknown function DUF1743; KEGG: pca:Pcar_2393 hypothetical protein.
 
     0.744
ACV24093.1
TIGRFAM: methanogenesis marker protein 2; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mpt:Mpe_A3475 hypothetical protein.
 
     0.721
ACV24203.1
PFAM: Mur ligase middle domain protein; KEGG: fph:Fphi_0316 D-alanyl-D-alanine-adding enzyme.
  
   
 0.720
ACV24222.1
TIGRFAM: methanogenesis marker protein 7; PFAM: Protein of unknown function UCP019164.
 
     0.718
ACV24756.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
   
 0.717
ACV25124.1
TIGRFAM: methanogenesis marker protein 5; PFAM: conserved hypothetical protein.
  
     0.709
ACV25205.1
TIGRFAM: methanogenesis marker 13 metalloprotein.
  
   
 0.709
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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