Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ACV23866.1PFAM: UspA domain protein; KEGG: aci:ACIAD1238 hypothetical protein. (146 aa)    
Predicted Functional Partners:
ACV23924.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: dma:DMR_13800 two-component hybrid sensor and regulator.
  
  
 0.844
ACV24569.1
Hypothetical protein.
   
    0.821
engB
GTP-binding protein HSR1-related; Necessary for normal cell division and for the maintenance of normal septation.
 
 
 
 0.717
gap
Glyceraldehyde-3-phosphate dehydrogenase, type II; KEGG: ajs:Ajs_2165 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase.
  
  
 0.654
ACV24902.1
PFAM: amidohydrolase; KEGG: cbc:CbuK_1316 chlorohydrolase/deaminase family protein.
     
 0.611
ACV24402.1
PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: acp:A2cp1_3392 protein of unknown function DUF190.
  
  
 0.569
ACV25334.1
TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: cjj:CJJ81176_0853 methylated-DNA--protein-cysteine S-methyltransferase.
  
  
 0.553
pgk
PFAM: phosphoglycerate kinase; KEGG: ade:Adeh_1531 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 0.534
ACV25210.1
AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
  
    0.511
ACV25220.1
Serine protease-like protein; KEGG: gur:Gura_1917 ATP-dependent protease La; Belongs to the peptidase S16 family.
       0.501
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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