Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23871.1Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: viral A-type inclusion protein. (438 aa)    
Predicted Functional Partners:
ACV23874.1
PFAM: THUMP domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: vvy:VV0873 thiamine biosynthesis protein ThiI.
 
     0.935
secF
SecD/SecF/SecDF export membrane protein; Involved in protein export.
 
     0.886
ACV23872.1
PFAM: Glycosyltransferase 28 domain; KEGG: rhi:NGR_b12360 membrane-anchored protein.
 
    0.862
cofD
LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
  
    0.799
ACV25359.1
Hypothetical protein; KEGG: eea-1; EEA1 (Early Endosome Antigen, Rab effector) homolog; K12478 early endosome antigen 1.
  
     0.719
ACV24411.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: nam:NAMH_1652 oligosaccharyl transferase, STT3 subunit.
  
     0.670
ACV25067.1
PFAM: zinc/iron permease; KEGG: transmembrane protein.
  
     0.654
ACV24064.1
S-layer domain protein-like protein.
  
     0.642
ACV23931.1
PFAM: Type II secretion system F domain.
  
     0.639
ACV24894.1
PFAM: protein of unknown function DUF95 transmembrane; KEGG: RNA methyltransferase, TrmH family protein.
  
     0.638
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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