Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23913.1TIGRFAM: methanogenesis marker protein 11; PFAM: domain of unknown function DUF1743; KEGG: pca:Pcar_2393 hypothetical protein. (300 aa)    
Predicted Functional Partners:
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp).
  
    0.903
ACV23914.1
PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: vha:VIBHAR_01513 hypothetical protein.
       0.849
ACV23911.1
PFAM: Protein of unknown function DUF1621; KEGG: hypothetical protein.
       0.789
ACV23912.1
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: dde:Dde_0062 GTP-binding protein EngA.
       0.779
ACV23856.1
TIGRFAM: methanogen marker protein 4.
 
     0.744
ACV24754.1
TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C.
 
     0.732
ACV24222.1
TIGRFAM: methanogenesis marker protein 7; PFAM: Protein of unknown function UCP019164.
  
     0.726
ACV25124.1
TIGRFAM: methanogenesis marker protein 5; PFAM: conserved hypothetical protein.
  
     0.722
ACV24532.1
TIGRFAM: methanogenesis marker protein 6; PFAM: conserved hypothetical protein.
  
     0.720
ACV24756.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.720
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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