Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23917.1PFAM: helix-turn-helix HxlR type; KEGG: ppd:Ppro_1054 HxlR family transcriptional regulator. (106 aa)    
Predicted Functional Partners:
ACV23916.1
Chromosome partitioning ATPase-like protein; KEGG: tbd:Tbd_1928 flagellar biosynthesis switch protein.
 
     0.971
ACV25359.1
Hypothetical protein; KEGG: eea-1; EEA1 (Early Endosome Antigen, Rab effector) homolog; K12478 early endosome antigen 1.
  
     0.690
ACV25067.1
PFAM: zinc/iron permease; KEGG: transmembrane protein.
 
     0.632
ACV23931.1
PFAM: Type II secretion system F domain.
  
     0.568
ACV23871.1
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: viral A-type inclusion protein.
  
     0.562
ACV25034.1
PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: gem:GM21_2431 FG-GAP repeat protein.
  
     0.558
ACV24889.1
KEGG: mxa:MXAN_7399 hypothetical protein.
  
     0.553
ACV24785.1
TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; KEGG: dol:Dole_0740 CRISPR-associated RAMP Csm5 family protein.
  
     0.509
ACV24134.1
PFAM: regulatory protein LysR; KEGG: pin:Ping_2047 transcriptional regulator, substrate-binding of LysR family protein.
 
  
 0.502
ACV23918.1
PFAM: Protein of unknown function UPF0113.
       0.499
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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