Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23922.1PFAM: protein of unknown function DUF126; KEGG: mlo:mll1736 hypothetical protein; Belongs to the UPF0107 family. (129 aa)    
Predicted Functional Partners:
ACV25225.1
PFAM: protein of unknown function DUF521; KEGG: bcm:Bcenmc03_6224 hypothetical protein.
 
 
 0.999
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
  0.902
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
       0.887
ACV24123.1
TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: bpy:Bphyt_2187 UbiD family decarboxylase.
 
     0.698
ACV24964.1
PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mxa:MXAN_6449 B12 binding/radical SAM domain-containing protein.
       0.608
ACV23921.1
TIGRFAM: small GTP-binding protein; PFAM: Nucleolar GTP-binding-1 domain protein; GTP-binding protein HSR1-related; Miro domain protein; KEGG: nucleolar GTP-binding protein.
       0.606
ACV23924.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: dma:DMR_13800 two-component hybrid sensor and regulator.
  
    0.533
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
       0.513
ACV24251.1
Aspartate/glutamate/uridylate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
 
     0.478
tmk
KEGG: wpi:WPa_0905 thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: thymidylate kinase.
       0.450
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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