STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV23942.1PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sdn:Sden_1162 thiamine pyrophosphate enzyme-like TPP-binding. (188 aa)    
Predicted Functional Partners:
ACV23943.1
KEGG: scl:sce7306 hypothetical protein.
  
 0.999
ACV25203.1
PFAM: Malate/L-lactate dehydrogenase; KEGG: sat:SYN_02526 malate/L-lactate dehydrogenase.
    
 0.977
ACV23944.1
PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: phosphosulfolactate synthase.
  
  
 0.758
taw1
Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
       0.751
ACV24773.1
PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: hso:HS_1737 DNA topoisomerase III.
  
    0.699
ACV23940.1
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: pca:Pcar_1215 hypothetical protein.
       0.689
ACV24633.1
KEGG: cbs:COXBURSA331_A1552 2-phosphosulfolactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase.
      
 0.640
ACV24754.1
TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C.
      
 0.632
ACV24978.1
PFAM: cobalamin synthesis protein P47K; KEGG: glo:Glov_1036 cobalamin synthesis protein P47K.
     
 0.615
ACV24977.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: glo:Glov_1037 ABC transporter related.
       0.609
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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