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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV23942.1PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sdn:Sden_1162 thiamine pyrophosphate enzyme-like TPP-binding. (188 aa)    
Predicted Functional Partners:
ACV23943.1
KEGG: scl:sce7306 hypothetical protein.
  
 0.999
ACV25203.1
PFAM: Malate/L-lactate dehydrogenase; KEGG: sat:SYN_02526 malate/L-lactate dehydrogenase.
    
 0.948
ACV23944.1
PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: phosphosulfolactate synthase.
  
  
 0.815
taw1
Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
       0.754
ACV24773.1
PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: hso:HS_1737 DNA topoisomerase III.
  
    0.718
ACV23940.1
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: pca:Pcar_1215 hypothetical protein.
       0.689
ACV24772.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: abu:Abu_1156 acetolactate synthase 3 catalytic subunit; Belongs to the TPP enzyme family.
     
 0.508
ACV24540.1
PFAM: Lactate/malate dehydrogenase; KEGG: ama:AM564 malate dehydrogenase; Belongs to the LDH/MDH superfamily.
     
  0.499
htpX
PFAM: peptidase M48 Ste24p; KEGG: dvm:DvMF_0946 peptidase M48 Ste24p; Belongs to the peptidase M48B family.
   
    0.493
ACV24898.1
TIGRFAM: hisA/hisF family protein; PFAM: histidine biosynthesis protein; KEGG: mei:Msip34_1494 histidine biosynthesis protein; Belongs to the HisA/HisF family.
       0.456
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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