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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV23948.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: glo:Glov_1181 4Fe-4S ferredoxin iron-sulfur binding domain protein. (144 aa)    
Predicted Functional Partners:
ACV25047.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: vap:Vapar_5615 fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 
 0.807
ACV24856.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cjr:CJE0873 quinol dehydrogenase membrane component.
  
 
 0.641
eif1a
Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
   
 0.633
ACV23946.1
TIGRFAM: coenzyme F420-reducing hydrogenase delta subunit; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: sfu:Sfum_2220 hydrogenase maturation protease.
     
 0.549
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.546
radB
DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.
       0.542
ACV24079.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dps:DP1013 methylviologen-reducing hydrogenase, alpha chain.
  
  
 0.508
ACV25051.1
Contains selenocysteine; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: gem:GM21_3972 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 0.508
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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