Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23972.1PFAM: GTP-binding protein HSR1-related; KEGG: similar to CG3983-PB, isoform B. (367 aa)    
Predicted Functional Partners:
ACV23921.1
TIGRFAM: small GTP-binding protein; PFAM: Nucleolar GTP-binding-1 domain protein; GTP-binding protein HSR1-related; Miro domain protein; KEGG: nucleolar GTP-binding protein.
  
 
 0.974
ACV23949.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: SnoRNA binding domain containing protein.
  
 
 0.944
rpl30
TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: 60S RIBOSOMAL PROTEIN L7; K02937 large subunit ribosomal protein L7e.
   
 
 0.930
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 0.925
rps8e
TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: rps8-1; 40S ribosomal protein S8; K02995 small subunit ribosomal protein S8e.
   
 
 0.923
ACV25055.1
TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; KEGG: hypothetical protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
 
 0.922
rlmE
Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
 
 0.921
ACV25187.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
  
 
 0.920
truB
rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
 
 
 0.918
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.915
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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