Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV23979.1PFAM: peptidylprolyl isomerase FKBP-type; KEGG: gme:Gmet_3146 peptidylprolyl isomerase, FKBP-type. (153 aa)    
Predicted Functional Partners:
ACV24854.1
PFAM: DsrE family protein; SirA family protein; KEGG: pca:Pcar_0429 uncharacterized NAD(FAD)-dependent dehydrogenase.
     
 0.641
ACV24803.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: hch:HCH_00076 hydrogenase accessory protein HypB.
    
 
 0.631
ACV24978.1
PFAM: cobalamin synthesis protein P47K; KEGG: glo:Glov_1036 cobalamin synthesis protein P47K.
    
 
 0.631
rps10
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
  
 0.600
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: hypothetical protein; Belongs to the eukaryotic ribosomal protein eS1 family.
   
    0.596
tuf
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
   
  
 0.511
rps28e
PFAM: Ribosomal protein S28e; KEGG: 40S ribosomal protein S28; K02979 small subunit ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
    0.502
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
  
  
 0.481
ACV23967.1
KEGG: ppd:Ppro_2794 NADH dehydrogenase (ubiquinone), 30 kDa subunit.
    
 
 0.460
ACV24169.1
KEGG: dds:Ddes_1885 NADH dehydrogenase (quinone).
    
 
 0.460
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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