Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ACV23988.1KEGG: dal:Dalk_1380 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components. (378 aa)    
Predicted Functional Partners:
ACV25115.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dal:Dalk_1379 binding-protein-dependent transport systems inner membrane component.
 
 0.999
ACV25116.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gur:Gura_3876 ABC transporter related.
 
 0.999
ACV24428.1
PFAM: nitrogen regulatory protein P-II; KEGG: abu:Abu_0198 nitrogen regulatory protein PII; Belongs to the P(II) protein family.
   
 
 0.787
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
  
 0.637
ACV24046.1
Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein.
 
     0.615
ribL
Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
       0.524
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
       0.507
ACV24667.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.451
ACV24796.1
TIGRFAM: siroheme synthase; PFAM: TrkA-N domain protein; KEGG: tdn:Suden_1977 siroheme synthase CysG.
  
  
 0.417
eif1a
Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
    0.406
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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