Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24017.1PFAM: glutamate synthase alpha subunit domain protein; KEGG: dde:Dde_1816 glutamate synthase (NADPH) GltB3 subunit. (258 aa)    
Predicted Functional Partners:
ACV24019.1
PFAM: glutamine amidotransferase class-II; KEGG: dde:Dde_1815 glutamate synthase (NADPH) GltB1 subunit.
  
 0.998
ACV24016.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2982 coenzyme F420 hydrogenase.
  
    0.995
ACV24018.1
PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvu:DVU1823 glutamate synthase, iron-sulfur cluster-binding subunit, putative; Belongs to the glutamate synthase family.
 
    0.994
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
    0.712
ACV24054.1
PFAM: ferredoxin-dependent glutamate synthase; KEGG: sfu:Sfum_4067 ferredoxin-dependent glutamate synthase.
 
    0.572
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: hypothetical protein; Belongs to the eukaryotic ribosomal protein eS1 family.
   
    0.536
pdxT
SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.511
ACV24191.1
PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sat:SYN_00800 ferridoxin.
 
     0.418
ACV23995.1
KEGG: mca:MCA2857 formylmethanofurane dehydrogenase subunit, putative; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein.
  
     0.412
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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