Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24018.1PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvu:DVU1823 glutamate synthase, iron-sulfur cluster-binding subunit, putative; Belongs to the glutamate synthase family. (510 aa)    
Predicted Functional Partners:
ACV24019.1
PFAM: glutamine amidotransferase class-II; KEGG: dde:Dde_1815 glutamate synthase (NADPH) GltB1 subunit.
 
 
 0.996
ACV24017.1
PFAM: glutamate synthase alpha subunit domain protein; KEGG: dde:Dde_1816 glutamate synthase (NADPH) GltB3 subunit.
 
    0.994
ACV24016.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2982 coenzyme F420 hydrogenase.
  
  
 0.956
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
 
 0.912
ACV24427.1
TIGRFAM: ammonium transporter; PFAM: ammonium transporter; KEGG: gem:GM21_1136 Rh family protein/ammonium transporter.
 
  
 0.669
tfb
Transcription factor TFIIB cyclin-related; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
    
   0.664
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.651
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.602
ACV24768.1
PFAM: glutamate synthase alpha subunit domain protein; KEGG: gsu:GSU1235 hypothetical protein.
 
 
 0.568
ACV23995.1
KEGG: mca:MCA2857 formylmethanofurane dehydrogenase subunit, putative; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein.
 
 
 0.560
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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