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cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (253 aa)    
Predicted Functional Partners:
ACV24137.1
GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein; KEGG: ara:Arad_0036 nucleotidyltransferase protein.
 
  
 0.977
ACV24987.1
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: stm:STM2027 precorrin-3B C17-methyltransferase.
  
  
 0.931
ACV24616.1
TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cvi:CV_1562 precorrin-3B C17-methyltransferase.
 
  
 0.930
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.926
ACV24147.1
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: abu:Abu_2184 hypothetical protein; Belongs to the UPF0284 family.
 
  
 0.904
ACV24852.1
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gme:Gmet_0482 precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase.
 
  
 0.895
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
  
 0.870
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.870
ACV24359.1
TIGRFAM: alpha-ribazole phosphatase CobZ; PFAM: phosphatidylglycerophosphatase A; KEGG: hpa:HPAG1_0721 phosphatidylglycerophosphatase A.
 
  
 0.848
ACV24022.1
TIGRFAM: HAD superfamily (subfamily IA) hydrolase, TIGR02253; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: fph:Fphi_0258 phosphoglycolate phosphatase.
       0.833
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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