STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ACV24040.14Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (151 aa)    
Predicted Functional Partners:
cdhC
CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
  
  
 0.995
ACV24041.1
TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; PFAM: CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit.
  
    0.987
cdhE
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
    0.931
ACV24435.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dal:Dalk_1102 cobyrinic acid ac-diamide synthase.
  
  
 0.928
cdhD
CO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
    0.927
cdhA
CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
  
  
 0.838
ACV24071.1
PFAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; KEGG: dol:Dole_2101 aldehyde ferredoxin oxidoreductase.
   
 
 0.759
ACV23894.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1419 NADH dehydrogenase subunit I.
  
 
 0.743
ACV25181.1
TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein; KEGG: dal:Dalk_1024 acetyl coenzyme A synthetase (ADP forming), alpha domain protein.
      
 0.641
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.542
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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