Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24049.1PFAM: protein of unknown function DUF167; KEGG: sfu:Sfum_4080 protein of unknown function DUF167; Belongs to the UPF0235 family. (98 aa)    
Predicted Functional Partners:
ACV24048.1
PFAM: Radical SAM domain protein; KEGG: afw:Anae109_0183 radical SAM domain-containing protein.
       0.981
ACV25098.1
PFAM: TOPRIM domain protein; SMART: Toprim sub domain protein; Belongs to the UPF0292 family.
 
     0.733
trmY
Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
 
     0.653
glyS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly).
       0.595
ACV24047.1
TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: noc:Noc_0259 S6 modification enzyme RimK.
       0.560
ACV23856.1
TIGRFAM: methanogen marker protein 4.
  
     0.559
ACV24203.1
PFAM: Mur ligase middle domain protein; KEGG: fph:Fphi_0316 D-alanyl-D-alanine-adding enzyme.
 
     0.462
ACV24070.1
TIGRFAM: riboflavin synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase.
 
     0.425
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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