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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ACV24056.1KEGG: sat:SYN_01933 prephenate dehydrogenase. (445 aa)    
Predicted Functional Partners:
ACV24085.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: nmu:Nmul_A2192 chorismate mutase.
 
 0.991
ACV24259.1
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: bas:BUsg379 P-protein.
 
 
 0.980
ACV24643.1
PFAM: aminotransferase class I and II; KEGG: nis:NIS_0815 aspartate aminotransferase.
    
 0.922
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Allinase-like; aminotransferase class V; KEGG: dal:Dalk_0935 histidinol-phosphate aminotransferase.
    
 0.921
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.820
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.792
ACV24057.1
Hypothetical protein; KEGG: cja:CJA_3182 putative PAP2 superfamily.
       0.732
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
   
 0.722
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
   
 0.716
aroK
TIGRFAM: shikimate kinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: cco:CCC13826_1493 homoserine kinase.
 
     0.659
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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