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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24056.1KEGG: sat:SYN_01933 prephenate dehydrogenase. (445 aa)    
Predicted Functional Partners:
ACV24085.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: nmu:Nmul_A2192 chorismate mutase.
 
 0.982
ACV24259.1
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: bas:BUsg379 P-protein.
 
 
 0.973
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Allinase-like; aminotransferase class V; KEGG: dal:Dalk_0935 histidinol-phosphate aminotransferase.
    
 0.923
ACV24643.1
PFAM: aminotransferase class I and II; KEGG: nis:NIS_0815 aspartate aminotransferase.
    
 0.922
ACV24057.1
Hypothetical protein; KEGG: cja:CJA_3182 putative PAP2 superfamily.
       0.730
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.634
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
   
 0.598
hmd
Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
      
 0.591
ACV24058.1
PFAM: peptidase M50; KEGG: ftm:FTM_0537 metallopeptidase, M50B family.
       0.551
ACV24059.1
PFAM: Rhomboid family protein; KEGG: lch:Lcho_0665 rhomboid family protein.
       0.541
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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