Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24058.1PFAM: peptidase M50; KEGG: ftm:FTM_0537 metallopeptidase, M50B family. (191 aa)    
Predicted Functional Partners:
ACV24059.1
PFAM: Rhomboid family protein; KEGG: lch:Lcho_0665 rhomboid family protein.
       0.855
ACV24057.1
Hypothetical protein; KEGG: cja:CJA_3182 putative PAP2 superfamily.
 
   
 0.685
ACV24122.1
PFAM: chromosome segregation and condensation protein ScpA; KEGG: hypothetical protein LOC691864.
       0.621
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.609
ACV25159.1
TIGRFAM: TraB family protein; PFAM: TraB determinant protein; KEGG: dol:Dole_2685 TraB family protein.
       0.609
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: sat:SYN_00889 phosphoribosylaminoimidazole synthetase.
       0.608
ACV24060.1
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family.
       0.604
ACV25145.1
TIGRFAM: methanogenesis marker protein 1; PFAM: protein of unknown function DUF181; KEGG: ara:Arad_4540 hypothetical protein.
 
     0.569
ACV24056.1
KEGG: sat:SYN_01933 prephenate dehydrogenase.
       0.553
ACV24695.1
PFAM: CBS domain containing protein; peptidase M50; SMART: CBS domain containing protein; KEGG: afw:Anae109_3134 peptidase M50; Belongs to the peptidase M50B family.
     
 0.461
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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