Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24081.1KEGG: noc:Noc_0025 formylmethanofuran dehydrogenase; Contains selenocysteine; TIGRFAM: formylmethanofuran dehydrogenase subunit B; PFAM: molybdopterin oxidoreductase. (435 aa)    
Predicted Functional Partners:
ACV23997.1
TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: noc:Noc_0024 DNA/RNA non-specific endonuclease.
 
 0.998
ACV23998.1
PFAM: molydopterin dinucleotide-binding region; KEGG: cco:CCC13826_2031 putative Myb2 protein.
 
 
 0.998
ACV24080.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: atc:AGR_L_920 ferrodoxin-like protein.
  
   0.998
ACV23995.1
KEGG: mca:MCA2857 formylmethanofurane dehydrogenase subunit, putative; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein.
 
 0.997
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
 
 0.996
ACV24079.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dps:DP1013 methylviologen-reducing hydrogenase, alpha chain.
  
 
 0.994
ACV23999.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfu:Sfum_0821 response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
  0.993
ACV24000.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dat:HRM2_02010 Fdx4.
 
 0.993
ACV24076.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.989
ACV24078.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: gem:GM21_3973 NADH ubiquinone oxidoreductase 20 kDa subunit.
  
 
 0.985
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.