Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24086.1PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nis:NIS_1258 hypothetical protein. (228 aa)    
Predicted Functional Partners:
ACV24085.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: nmu:Nmul_A2192 chorismate mutase.
       0.981
ACV24087.1
Hypothetical protein.
       0.971
ACV24323.1
Hypothetical protein; KEGG: cjj:CJJ81176_1143 general glycosylation pathway protein.
  
    0.874
ACV24088.1
KEGG: amc:MADE_04062 type I site-specific restriction-modification system, R (restriction) subunit; PFAM: type III restriction protein res subunit; EcoEI R domain protein; protein of unknown function DUF450; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase.
       0.723
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
    
 0.722
ACV24089.1
PFAM: ATPase; SMART: AAA ATPase; KEGG: outer arm dynein beta heavy chain.
       0.656
rps9
TIGRFAM: ribosomal protein S9P; PFAM: ribosomal protein S9; KEGG: hypothetical protein; Belongs to the universal ribosomal protein uS9 family.
    
 0.612
ACV24093.1
TIGRFAM: methanogenesis marker protein 2; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mpt:Mpe_A3475 hypothetical protein.
       0.587
ACV24805.1
KEGG: similar to predicted protein; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1.
  
 0.568
rpl7ae
Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.541
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.