Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24093.1TIGRFAM: methanogenesis marker protein 2; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mpt:Mpe_A3475 hypothetical protein. (324 aa)    
Predicted Functional Partners:
pgk
PFAM: phosphoglycerate kinase; KEGG: ade:Adeh_1531 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
       0.859
ACV23856.1
TIGRFAM: methanogen marker protein 4.
 
     0.721
ACV24244.1
Conserved hypothetical protein.
 
     0.617
ACV25146.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gsu:GSU2799 radical SAM domain-containing protein.
       0.609
ACV24087.1
Hypothetical protein.
       0.601
ACV24091.1
PFAM: restriction modification system DNA specificity domain; KEGG: fph:Fphi_1525 type I restriction-modification system, subunit S.
       0.601
ACV24092.1
PFAM: N-6 DNA methylase; KEGG: ftn:FTN_1152 type I restriction-modification system, subunit M (methyltransferase).
       0.601
ACV25125.1
TIGRFAM: methanogenesis marker protein 3; Belongs to the UPF0288 family.
 
     0.601
ACV24086.1
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nis:NIS_1258 hypothetical protein.
       0.587
ACV24090.1
Hypothetical protein.
       0.567
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (14%) [HD]