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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
ACV24102.1PFAM: Transcription factor CBF/NF-Y/histone domain protein. (97 aa)    
Predicted Functional Partners:
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
       0.977
ACV24101.1
PFAM: phosphoribosyltransferase; KEGG: orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase; K00762 orotate phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.756
ACV24024.1
PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein); KEGG: cjd:JJD26997_0811 thermonuclease family protein.
      
 0.573
ACV24098.1
PFAM: protein of unknown function DUF125 transmembrane; KEGG: dps:DP2435 hypothetical protein.
     
 0.530
ACV24099.1
PFAM: Protein of unknown function DUF2115; Belongs to the UPF0305 family.
       0.524
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.524
ACV24097.1
PFAM: Dimethylmenaquinone methyltransferase; KEGG: dvm:DvMF_2302 dimethylmenaquinone methyltransferase.
       0.495
ACV24096.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gem:GM21_0410 porphobilinogen synthase; Belongs to the ALAD family.
       0.461
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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