Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24104.1PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: hypothetical protein. (536 aa)    
Predicted Functional Partners:
nep1
Suppressor Mra1 family protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
     0.561
ACV24687.1
PFAM: 4-vinyl reductase 4VR; Roadblock/LC7 family protein; KEGG: dat:HRM2_39440 hypothetical protein.
  
  
 0.559
ACV24876.1
PFAM: 4-vinyl reductase 4VR; KEGG: ppd:Ppro_0428 4-vinyl reductase, 4VR.
  
  
 0.553
ACV24926.1
PFAM: 4-vinyl reductase 4VR.
  
  
 0.553
ACV24375.1
PFAM: regulatory protein ArsR; transcriptional regulator TrmB; KEGG: dac:Daci_2400 ArsR family transcriptional regulator; Belongs to the GbsR family.
       0.501
albA
DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
  
     0.475
ACV25022.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
  
     0.448
ACV25023.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
  
     0.443
adkA
KEGG: bcs:BCAN_A0739 adenylate kinase.
  
     0.427
ACV25024.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
  
     0.410
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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