Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24108.1PFAM: protein of unknown function DUF62; KEGG: dal:Dalk_3152 protein of unknown function DUF62. (253 aa)    
Predicted Functional Partners:
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp).
       0.652
ACV24605.1
KEGG: dal:Dalk_3061 cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase.
     
 0.648
ACV23959.1
Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family.
       0.609
ACV24413.1
Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
       0.609
ACV24264.1
TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: ppr:PBPRB0776 putative adenylate cyclase CyaB.
 
     0.537
ACV24110.1
KEGG: sun:SUN_1954 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.403
ACV24111.1
PFAM: tyrosine protein kinase; RIO-like kinase; KEGG: nis:NIS_1524 hypothetical protein.
       0.403
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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