Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24113.1PFAM: protein of unknown function DUF324; KEGG: conserved hypothetical protein. (386 aa)    
Predicted Functional Partners:
ACV24114.1
PFAM: protein of unknown function DUF324; KEGG: DNA double-strand break repair Rad50 ATPase.
       0.921
ACV24116.1
TIGRFAM: CRISPR-associated protein, Csx11 family; KEGG: viral A-type inclusion protein.
       0.921
ACV24117.1
PFAM: protein of unknown function DUF324; KEGG: hypothetical protein.
       0.795
ACV24115.1
Hypothetical protein.
       0.773
ACV24118.1
KEGG: viral A-type inclusion protein.
       0.696
ACV24119.1
PFAM: protein of unknown function DUF324.
       0.696
ACV24112.1
PFAM: protein of unknown function DUF75.
       0.538
ACV24110.1
KEGG: sun:SUN_1954 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.478
ACV24111.1
PFAM: tyrosine protein kinase; RIO-like kinase; KEGG: nis:NIS_1524 hypothetical protein.
       0.478
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (20%) [HD]