STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24117.1PFAM: protein of unknown function DUF324; KEGG: hypothetical protein. (459 aa)    
Predicted Functional Partners:
ACV24114.1
PFAM: protein of unknown function DUF324; KEGG: DNA double-strand break repair Rad50 ATPase.
 
 
 
 0.996
ACV24789.1
TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: msu:MS1651 hypothetical protein.
 
 
 
 0.976
ACV24119.1
PFAM: protein of unknown function DUF324.
 
     0.970
ACV24116.1
TIGRFAM: CRISPR-associated protein, Csx11 family; KEGG: viral A-type inclusion protein.
 
     0.947
ACV24118.1
KEGG: viral A-type inclusion protein.
       0.885
ACV24113.1
PFAM: protein of unknown function DUF324; KEGG: conserved hypothetical protein.
       0.795
ACV25248.1
TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57.
 
   
 0.502
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.500
ACV24786.1
TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; PFAM: protein of unknown function DUF324; KEGG: hypothetical protein.
 
     0.464
ACV24115.1
Hypothetical protein.
       0.456
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.