Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24136.1PFAM: PRC-barrel domain protein. (88 aa)    
Predicted Functional Partners:
ACV24137.1
GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein; KEGG: ara:Arad_0036 nucleotidyltransferase protein.
  
    0.982
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
       0.922
ACV24134.1
PFAM: regulatory protein LysR; KEGG: pin:Ping_2047 transcriptional regulator, substrate-binding of LysR family protein.
       0.873
ACV24133.1
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ppd:Ppro_1936 methyltransferase type 11.
       0.739
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
    0.586
ACV24139.1
PFAM: photosystem I assembly BtpA; KEGG: ara:Arad_9790 hypothetical protein.
       0.554
ACV24140.1
PFAM: Glycosyl transferase, family 4, conserved region; KEGG: cje:Cj0433c phospho-N-acetylmuramoyl-pentapeptide-transferase.
       0.554
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
       0.554
hel308
DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
       0.495
ACV24142.1
PFAM: Protein of unknown function DUF530; KEGG: DNA double-strand break repair Rad50 ATPase; K02365 separase.
       0.489
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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