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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24142.1PFAM: Protein of unknown function DUF530; KEGG: DNA double-strand break repair Rad50 ATPase; K02365 separase. (486 aa)    
Predicted Functional Partners:
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.860
ACV24140.1
PFAM: Glycosyl transferase, family 4, conserved region; KEGG: cje:Cj0433c phospho-N-acetylmuramoyl-pentapeptide-transferase.
       0.722
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
    0.691
ACV24139.1
PFAM: photosystem I assembly BtpA; KEGG: ara:Arad_9790 hypothetical protein.
       0.683
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
    0.503
ACV24136.1
PFAM: PRC-barrel domain protein.
       0.489
ACV24137.1
GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein; KEGG: ara:Arad_0036 nucleotidyltransferase protein.
       0.489
ACV23957.1
PFAM: class II aldolase/adducin family protein; KEGG: hsm:HSM_1905 putative aldolase.
   
    0.465
ACV24133.1
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ppd:Ppro_1936 methyltransferase type 11.
       0.449
ACV24134.1
PFAM: regulatory protein LysR; KEGG: pin:Ping_2047 transcriptional regulator, substrate-binding of LysR family protein.
       0.449
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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