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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24173.1PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pol:Bpro_1155 binding-protein-dependent transport systems inner membrane component. (171 aa)    
Predicted Functional Partners:
ACV24394.1
PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; KEGG: gem:GM21_3877 TrkA-N domain protein.
  
    0.478
ACV24174.1
Hypothetical protein.
       0.463
ACV24084.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ftn:FTN_1526 dihydrolipoamide dehydrogenase.
 
   
 0.460
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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