Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ACV24183.1PFAM: protein of unknown function DUF75. (234 aa)    
Predicted Functional Partners:
ACV24184.1
PFAM: Protein of unknown function DUF473.
  
   0.982
ACV24873.1
TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; KEGG: sat:SYN_01643 Fe-S oxidoreductase.
  
    0.893
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
     0.811
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 
 0.726
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
     0.625
ACV24390.1
PFAM: Protein of unknown function DUF655.
 
     0.609
ACV24801.1
PFAM: Protein of unknown function DUF63.
  
     0.573
ACV24182.1
TIGRFAM: dihydropteroate synthase-related protein; PFAM: dihydropteroate synthase DHPS; KEGG: mei:Msip34_1684 dihydropteroate synthase DhpS.
       0.572
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.570
ACV25177.1
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: similar to multiprotein bridging factor 1 CG4143-PA, isoform A; K03627 putative transcription factor.
 
     0.570
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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