Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24186.1PFAM: N-6 DNA methylase; KEGG: cjr:CJE0310 D12 class N6 adenine-specific DNA methyltransferase, putative. (1012 aa)    
Predicted Functional Partners:
ACV24593.1
PFAM: restriction modification system DNA specificity domain; KEGG: hip:CGSHiEE_02145 hypothetical protein.
 
 
 0.849
ACV24091.1
PFAM: restriction modification system DNA specificity domain; KEGG: fph:Fphi_1525 type I restriction-modification system, subunit S.
 
 
 0.848
ACV24364.1
PFAM: N-6 DNA methylase; restriction modification system DNA specificity domain; KEGG: wsu:WS1649 DNA methylase-type I restriction-modification system.
  
 
 0.828
ACV24594.1
Type I site-specific deoxyribonuclease, HsdR family; KEGG: vfi:VF_A0539 type I restriction-modification system restriction subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase.
  
  
 0.729
ACV24088.1
KEGG: amc:MADE_04062 type I site-specific restriction-modification system, R (restriction) subunit; PFAM: type III restriction protein res subunit; EcoEI R domain protein; protein of unknown function DUF450; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase.
 
 
 0.706
ACV24187.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: hypothetical protein.
       0.581
ACV24185.1
TIGRFAM: DNA helicase; SMART: DEAD-like helicase; KEGG: nam:NAMH_1081 putative DNA helicase.
       0.487
ACV25096.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein.
  
    0.439
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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