Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24187.1PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: hypothetical protein. (433 aa)    
Predicted Functional Partners:
ACV25272.1
KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein.
   
    0.636
ACV23974.1
Formate hydrogenlyase subunit 4-like protein; KEGG: rhi:NGR_c10570 NADH dehydrogenase I chain H.
       0.596
ACV24186.1
PFAM: N-6 DNA methylase; KEGG: cjr:CJE0310 D12 class N6 adenine-specific DNA methyltransferase, putative.
       0.581
vapC
PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
    0.510
ACV25107.1
PFAM: THUMP domain protein; KEGG: ebw:BWG_0305 sulfurtransferase required for thiamine and 4-thiouridine biosynthesis.
  
     0.424
mtrC
Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.404
ACV24185.1
TIGRFAM: DNA helicase; SMART: DEAD-like helicase; KEGG: nam:NAMH_1081 putative DNA helicase.
       0.403
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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