Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
ACV24191.1PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sat:SYN_00800 ferridoxin. (131 aa)    
Predicted Functional Partners:
ACV24190.1
PFAM: protein of unknown function DUF39; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: sfu:Sfum_1059 protein of unknown function DUF39.
 
 
 0.999
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
  0.943
ACV24152.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rlt:Rleg2_5063 homoserine dehydrogenase.
     
  0.900
ACV24708.1
Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
     
  0.900
ACV25028.1
PFAM: Methionine synthase vitamin-B12 independent; Cobalamin-independent synthase MetE domain protein; KEGG: bau:BUAPTUC7_030 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
     
  0.900
ACV25328.1
PFAM: ApbE family lipoprotein; KEGG: sfu:Sfum_2124 hypothetical protein; Belongs to the UPF0280 family.
 
   
 0.882
ACV24794.1
TIGRFAM: methanogenesis marker 16 metalloprotein; PFAM: protein of unknown function DUF39; KEGG: dvm:DvMF_1464 protein of unknown function DUF39.
 
  
 0.779
srp54
GTP-binding signal recognition particle SRP54 G- domain protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.509
ACV24019.1
PFAM: glutamine amidotransferase class-II; KEGG: dde:Dde_1815 glutamate synthase (NADPH) GltB1 subunit.
 
     0.474
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
       0.463
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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