Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24194.1PFAM: Ion transport 2 domain protein; Ion transport protein; KEGG: similar to predicted protein. (211 aa)    
Predicted Functional Partners:
ACV24394.1
PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; KEGG: gem:GM21_3877 TrkA-N domain protein.
 
   
 0.897
ACV24193.1
PFAM: Cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: gur:Gura_0041 cobyric acid synthase CobQ.
  
    0.624
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
    0.612
ACV24195.1
PFAM: CBS domain containing protein; ParB domain protein nuclease; SMART: ParB domain protein nuclease; CBS domain containing protein; KEGG: similar to inosine-5-monophosphate dehydrogenase; K00088 IMP dehydrogenase.
       0.606
ACV24196.1
PFAM: Protein of unknown function DUF509; KEGG: hypothetical protein.
       0.598
ACV25322.1
TIGRFAM: small GTP-binding protein; PFAM: TGS domain protein; GTP-binding protein HSR1-related; KEGG: hypothetical protein.
  
  
 0.496
ACV24192.1
PFAM: protein of unknown function DUF114; KEGG: bbt:BBta_7800 hypothetical protein.
       0.475
ACV25342.1
TIGRFAM: L-seryl-tRNA(Sec) kinase; PFAM: Chromatin associated protein KTI12; KEGG: hypothetical protein.
  
    0.417
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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