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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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gene co-occurrence
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[Homology]
Score
ACV24196.1PFAM: Protein of unknown function DUF509; KEGG: hypothetical protein. (145 aa)    
Predicted Functional Partners:
ACV24126.1
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
    
 
 0.986
ACV24195.1
PFAM: CBS domain containing protein; ParB domain protein nuclease; SMART: ParB domain protein nuclease; CBS domain containing protein; KEGG: similar to inosine-5-monophosphate dehydrogenase; K00088 IMP dehydrogenase.
       0.981
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.762
hel308
DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
       0.609
ACV24194.1
PFAM: Ion transport 2 domain protein; Ion transport protein; KEGG: similar to predicted protein.
       0.598
ACV23882.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
       0.532
rps17e
KEGG: 40S ribosomal protein S17-A; K02962 small subunit ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
       0.501
ACV25188.1
PFAM: Protein of unknown function DUF2144.
      
 0.486
ACV23959.1
Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family.
       0.463
ACV24193.1
PFAM: Cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: gur:Gura_0041 cobyric acid synthase CobQ.
       0.448
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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