Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24211.1PFAM: Protein of unknown function, nitrogen regulatory protein PII-related. (108 aa)    
Predicted Functional Partners:
ACV24212.1
PFAM: protein of unknown function DUF134; Sigma-70 region 4 type 2; KEGG: sbn:Sbal195_1428 hypothetical protein; Belongs to the UPF0251 family.
  
    0.995
ACV24213.1
KEGG: ara:Arad_7321 peptide ABC transporter; TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter related; SMART: AAA ATPase.
  
    0.993
ACV24210.1
PFAM: Protein of unknown function, nitrogen regulatory protein PII-related.
      
0.755
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.451
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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