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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24212.1PFAM: protein of unknown function DUF134; Sigma-70 region 4 type 2; KEGG: sbn:Sbal195_1428 hypothetical protein; Belongs to the UPF0251 family. (118 aa)    
Predicted Functional Partners:
ACV24213.1
KEGG: ara:Arad_7321 peptide ABC transporter; TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter related; SMART: AAA ATPase.
  
    0.999
ACV24211.1
PFAM: Protein of unknown function, nitrogen regulatory protein PII-related.
  
    0.993
ACV24210.1
PFAM: Protein of unknown function, nitrogen regulatory protein PII-related.
  
    0.961
ACV24938.1
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: slo:Shew_3627 XRE family transcriptional regulator.
     
 0.871
ACV24561.1
DNA binding protein, Tfx family; Putative transcriptional regulator.
      
 0.868
ACV25171.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: dat:HRM2_42460 hypothetical protein.
 
  
 0.742
ACV25169.1
PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2264 cobyrinic acid ac-diamide synthase.
 
     0.575
ACV25170.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sat:SYN_01187 iron-sulfur cluster and nucleotide-binding protein.
 
     0.521
ACV24740.1
KEGG: sat:SYN_01979 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
       0.467
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.430
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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