Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24226.1PFAM: peptidase U32; KEGG: dat:HRM2_36490 peptidase (U32 family protein). (404 aa)    
Predicted Functional Partners:
ACV24224.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; ferredoxin; KEGG: ppd:Ppro_2541 hypothetical protein.
 
     0.790
ACV24225.1
TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: pmu:PM0428 hypothetical protein.
       0.768
ACV23894.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1419 NADH dehydrogenase subunit I.
  
 
 0.673
ACV24227.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nam:NAMH_0733 iron ABC transporter ATPase subunit.
       0.536
ACV24228.1
PFAM: transport system permease protein; KEGG: dol:Dole_1652 transport system permease protein.
     
 0.524
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
  
   0.497
ACV24229.1
PFAM: protein of unknown function DUF364; KEGG: pca:Pcar_0781 hypothetical protein.
       0.455
ACV24939.1
KEGG: hypothetical protein; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.420
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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