Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24232.1PFAM: periplasmic binding protein; KEGG: pca:Pcar_3056 ABC-type Fe3+-hydroxamate transport system, periplasmic component. (370 aa)    
Predicted Functional Partners:
ACV24227.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nam:NAMH_0733 iron ABC transporter ATPase subunit.
 
 
 0.980
ACV24228.1
PFAM: transport system permease protein; KEGG: dol:Dole_1652 transport system permease protein.
 
 
 0.943
ACV24950.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppd:Ppro_1258 ABC transporter related.
  
 
 0.882
ACV24376.1
PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: dal:Dalk_3123 formylmethanofuran dehydrogenase subunit E region.
 
    0.838
ACV24231.1
Hypothetical protein; KEGG: pca:Pcar_0859 QbsJ-like methyltransferase.
 
    0.780
ACV24951.1
PFAM: transport system permease protein; KEGG: ppd:Ppro_1257 transport system permease protein.
 
 
 0.767
ACV24952.1
PFAM: transport system permease protein; KEGG: ppd:Ppro_1257 transport system permease protein.
 
 
 0.754
ACV24233.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dal:Dalk_3602 cobyrinic acid ac-diamide synthase.
 
     0.706
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
  
  
 0.469
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.469
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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