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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24234.1Transcriptional regulator NikR, CopG family; PFAM: CopG domain protein DNA-binding domain protein; NikR nickel binding; KEGG: cff:CFF8240_0934 nickel responsive regulator. (126 aa)    
Predicted Functional Partners:
ACV24235.1
PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: ade:Adeh_3266 ATPase AAA-5.
       0.788
ACV24236.1
Hypothetical protein.
       0.788
ACV24909.1
PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dat:HRM2_01850 RecJ-like exonuclease (DnaJ-type Zn finger protein).
 
   
 0.592
ACV24832.1
TIGRFAM: methanogenesis marker protein 14; PFAM: conserved hypothetical protein.
  
     0.589
ACV24639.1
TIGRFAM: methanogenesis marker protein 9.
  
     0.578
ACV24419.1
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: DNA double-strand break repair Rad50 ATPase; K02349 DNA polymerase theta subunit.
  
     0.513
mtrH
Tetrahydromethanopterin S-methyltransferase, MtrH subunit; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
     0.481
ACV24751.1
TIGRFAM: methanogenesis marker protein 10; PFAM: protein of unknown function DUF512; Radical SAM domain protein; KEGG: dal:Dalk_1728 glycyl-radical enzyme activating protein family.
  
     0.477
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
   
 0.474
mtrE
Tetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.462
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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