Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24246.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (297 aa)    
Predicted Functional Partners:
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
 
 0.921
ACV23894.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1419 NADH dehydrogenase subunit I.
  
 
 0.862
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
  
 0.787
ACV24212.1
PFAM: protein of unknown function DUF134; Sigma-70 region 4 type 2; KEGG: sbn:Sbal195_1428 hypothetical protein; Belongs to the UPF0251 family.
  
    0.625
ACV24909.1
PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dat:HRM2_01850 RecJ-like exonuclease (DnaJ-type Zn finger protein).
  
 0.612
ACV25231.1
TIGRFAM: hydrogenase maturation protease HycI; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: ppd:Ppro_0598 hydrogenase maturation protease.
     
 0.612
ACV25170.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sat:SYN_01187 iron-sulfur cluster and nucleotide-binding protein.
 
 
 
 0.597
ACV24939.1
KEGG: hypothetical protein; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.588
ACV25272.1
KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein.
   
 0.554
ACV25171.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: dat:HRM2_42460 hypothetical protein.
 
  
 0.547
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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