Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rps27ePFAM: Ribosomal protein S27E; KEGG: YALI0E34826p. (61 aa)    
Predicted Functional Partners:
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
  
 
 0.999
rps17e
KEGG: 40S ribosomal protein S17-A; K02962 small subunit ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
 
 
 0.997
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
 0.994
rpl15e
PFAM: Ribosomal protein L15e; KEGG: 60S ribosomal protein L15 (RPL15B); K02877 large subunit ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
   
 
 0.993
rps24e
PFAM: Ribosomal protein S24e; KEGG: ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
 0.992
rpl18e
PFAM: ribosomal protein L15; KEGG: 60S ribosomal protein L18; K02883 large subunit ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
 
 0.988
ACV24513.1
PFAM: Protein of unknown function DUF1610.
  
   0.988
rpl31e
PFAM: Ribosomal protein L31e; KEGG: similar to ribosomal protein L31; K02910 large subunit ribosomal protein L31e.
 
 
 0.979
rpl21e
PFAM: Ribosomal protein L21e; KEGG: 60S ribosomal protein L21; K02889 large subunit ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 
 0.979
rps13
Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
   
   0.978
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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